Endocrine Abstracts

Aldosterone/renin ratio (ARR) is obtained by measurements of plasma aldosterone (ALD) and either plasma renin activity (PRA) or direct renin concentration (DRC). The various gestogen components (desogestrel, DSG; gestoden, GD; drospirenon, DRSP) of the frequently used oral contraceptives (OC) can influence the ARRs differently. Aim of the study was to analyze the effect of OCs with different gestogens and low-dose estradiol component on ARRs (ALD/PRA versus ALD/DRC).<p cla...

Plasma total testosterone (TT) does not provide reliable information about the biological active testosterone, since a large proportion of this hormone is bound to either specific (sex hormone binding globulin, SHBG) or non-specific binding proteins (albumin). Free testosterone (fT) represents not more than 0.7–2.2% of TT while bioavailable testosterone (BA-T) in females is about 15–48% of the TT. The aim was to investigate the analytical and clinical correlations am...

Introduction: Human tear is rich in cytokines, i.e. in healthy individuals it exhibits a higher ratio of cytokines to total proteins than that in the serum of the same individual. EOP related to Graves–Basedow disease is thought to develop due to elevation of serum cytokine levels and to an altered cytokine response of the intra- and periorbital tissues. In our present study we focused on the measurement of IL6, IL8 and TNF-α, the relative amount of a lipocalin-type ...

Background: The most reliable biochemical markers in the follow-up of medullary thyroid carcinoma (MTC) are serum calcitonin (CAL) and carcinoembrional antigen (CEA).Case: A 82 years male presented with rapidly growing neck tumour in April 2008. The patient underwent total thyroidectomy with lymph node dissection (June 2008). The pathology revealed MTC localized only in the left lobe (pT3NoMx), the immunohistology showed CAL-, synaptophysin, chromogranin...